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Acid phosphatase determination in vaginal fluid

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Like all enzymes, it is needed to trigger specific chemical reactions. Acid phosphatase testing is done to diagnose whether prostate cancer has spread to other parts of the body metastasized , and to check the effectiveness of treatment. The test has been largely supplanted by the prostate specific antigen test PSA. The male prostate gland has times more acid phosphatase than any other body tissue.
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Prostatic acid phosphatase. Current assessment in vaginal fluid of alleged rape victims.

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Prostatic acid phosphatase. Current assessment in vaginal fluid of alleged rape victims.

The presence of semen in vaginal fluid, as identified by an acid phosphatase spot test, does not influence vaginal proinflammatory cytokine concentrations. Objective : determine whether semen, as detected by acid phosphatase, influences vaginal cytokines or secretory leukocyte protease inhibitor concentrations. Methods : pregnant women had vaginal fluid collected for Gram stain, acid phosphatase detection by colorimetric assay, and interleukin 1-Beta, interleukin-6, interleukin-8, and secretory leukocyte protease inhibitor measurement by enzyme immunoassay. Results for women with and without acid phosphatase were compared by Mann-Whitney test. There were no significant differences in proinflammatory cytokine concentrations; however, secretory leukocyte protease inhibitor concentrations were significantly higher among women with acid phosphatase. Conclusions : proinflammatory cytokine measurement does not appear to be affected by the presence of semen, but secretory leukocyte protease inhibitor is significantly higher when semen is present.
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Effect of Semen on Vaginal Fluid Cytokines and Secretory Leukocyte Protease Inhibitor

Javascript is currently disabled in your browser. Several features of this site will not function whilst javascript is disabled. Authors Harbison S , Fleming R. Received 8 July Published 10 February Volume Pages 11—
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Learn something new every day More Info Acid phosphatase ACP is a type of enzyme manufactured by the body. Like all enzymes , it is composed of specialized proteins that catalyze, or stimulate, certain biological reactions. ACP is classified as a hydrolase enzyme because its purpose is to catalyze the hydrolysis of a chemical bond.
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